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Toprol-xl, metoprolol succinate, is a beta 1 -selective cardioselective adrenoceptor blocking agent, for oral administration, available as extended-release tablets.

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Animal and human experiments indicate that metoprolol slows the sinus rate and decreases av nodal conduction.

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Patients with contraindications to treatment during the early phase of suspected or definite myocardial infarction, patients who appear not to tolerate the full early treatment, and patients in whom the physician wishes to delay therapy for any other reason should be started on metoprolol tablets as soon as their clinical condition allows.

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